I think it really depends on the individual. There are some people who wouldn't think twice about walking up to people they don't know, introducing themselves, making new friends and so on. It wouldn't matter if they were in a place with 10 people or 10,000. At the other extreme are people who are much more cautious, and may feel awkward not knowing anyone. They might not put themselves forward, and then if no one approaches them then they might leave without making new friends.
I think it helps to go to any con or local meet with an attitude of "I'm going to introduce myself to people I don't know" if I'm interested in what they're doing. Once you know a few people, or fall in with a small group, you tend to meet others much more easily. If you know someone else who is going, or you've at least chatted to them online, it makes it a bit easier.
If you do decide to attend ConFuzzled, then you'll probably appreciate our "First Con" event that runs right after the opening ceremony, and perhaps joining in a team at our furry Pub Quiz on the first night. Meanwhile, tell us all a bit about yourself, maybe post to the "How you found furry" thread.